Martino D, Strejilevich S, Torralva T, Manes F.  Decision making in euthymic bipolar I and bipolar II disorders. Psychological Medicine 2010

Decision making in euthymic bipolar I and bipolar II disorders.

Autores Martino D, Strejilevich S, Torralva T, Manes F. 
Año 2010
Journal  Martino D, Strejilevich S, Torralva T, Manes F. 
Volumen 41(6):1319-27
Abstract  BACKGROUND: The main aim of this study was to compare a large population of patients with bipolar disorder (BD) types I and II strictly defined as euthymic with healthy controls on measures of decision making. An additional aim was to compare performance on a decision-making task between patients with and without a history of suicide attempt.MethodEighty-five euthymic patients with BD-I or BD-II and 34 healthy controls were included. All subjects completed tests to assess verbal memory, attention and executive functions, and a decision-making paradigm (the Iowa Gambling Task, IGT). RESULTS: Both groups of patients had worse performance than healthy controls on measures of verbal memory, attention and executive function. No significant differences were found between BD-I, BD-II and healthy controls on measures of decision making. By contrast, patients with a history of suicide attempt had lower performance in the IGT than patients without a history of suicide attempt. CONCLUSIONS: Patients with euthymic BD-I and BD-II had intact decision-making abilities, suggesting that this does not represent a reliable trait marker of the disorder. In addition, our results provide further evidence of an association between impairments in decision making and vulnerability to suicidal behavior.
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