Kim SH, Manes F, Kosier T, Baruah S, Robinson RG.  Irritability following traumatic brain injury. The Journal of nervous and mental disease 1999

Irritability following traumatic brain injury.

Autores Kim SH, Manes F, Kosier T, Baruah S, Robinson RG. 
Año 1999
Journal  Kim SH, Manes F, Kosier T, Baruah S, Robinson RG. 
Volumen 187(6): 327-335
Abstract  This study was undertaken to identify the clinical and pathoanatomical correlates of irritability in patients with closed head injuries. A consecutive series of 66 patients was assessed in hospital and at 3, 6, 9, and 12-month follow-ups. Patients fulfilling criteria for irritability were divided into 2 groups based on the immediate or delayed onset of their irritability and compared with patients without irritability for background characteristics, impairment variables, and lesion characteristics. There were 12 patients (18.2%) with acute onset irritability and 10 (15.1%) with delayed onset irritability. Acute onset irritability patients had a higher frequency of left cortical lesions. Delayed onset irritability patients showed a strong association with poor social functioning and greater impairment in activities of daily living. The findings suggest that post-brain injury irritability may have different causes and treatment in the acute and chronic stages.
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