An MRI study of the corpus callosum and cerebellum in mentally retarded autistic individuals.
|Autores||Manes F, Piven J, Lic. Daniela Vrancic, Nanclares V, Plebst C, Starkstein S.|
|Journal||Manes F, Piven J, Lic. Daniela Vrancic, Nanclares V, Plebst C, Starkstein S.|
|Abstract||The areas of seven subregions of the corpus callosum and three subregions of the cerebellum were examined on midsagittal magnetic resonance imaging scans of 27 low-IQ autistic individuals and 17 nonautistic individuals of comparable mental age. Autistic individuals had a significantly smaller corpus callosum (most marked in the body). No significant between-group differences were found in cerebellum areas. Results demonstrate that abnormalities of the corpus callosum reported in high-functioning autistic individuals are also present in autistic individuals with mental retardation and extend previous reports showing no evidence for a selective hypoplasia of cerebellar lobules VI-VII.|