Categoría: Papers con abstracts

Crespo-Facorro B, Manes F, Plebst C, Morcuende M.  Neuropsychiatric effects of insular stroke. Biological markers of schizophrenic symptoms: functional neuroimaging. Actas luso-españolas de neurología, psiquiatría y ciencias afines 1998

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Despite heterogeneous phenotype, lack of pathognomonic symptoms and great variability of symptoms during the course of the illness, functional neuroimaging studies have showed specific patterns of activation associated to particular schizophrenic symptoms or symptom dimensions. Negative symptoms have been associated to hypofrontality; auditory hallucinations seem to be related to abnormalities in brain regions involved in language and, reality distortion dimension has been associated to left temporal lobe impairments.

Chemerinski E, Petracca G, Manes F, Leiguarda R, Starkstein S.  Prevalence and correlates of anxiety in Alzheimer’s disease. Depression and anxiety 1998

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We assessed a consecutive series of 398 patients with probable Alzheimer’s disease (AD) for the presence of Generalized Anxiety Disorder (GAD) using a standardized neuropsychiatric evaluation. Five percent of patients showed GAD during the 4 weeks preceding the psychiatric evaluation. AD patients with GAD showed significantly higher scores of depression, irritability, overt aggression, mania, and pathological crying than AD patients without GAD. The most severe symptoms of anxiety were those of tension, fears, insomnia, and physical complaints.