Capacitación intensiva presencial en Mindfulness para profesionales, herramientas para cultivar el bienestar.

Fecha de inicio: Lunes 19/02 al viernes 23/02

Duración: 5 encuentros + 1 jornada intensiva

Jornada Intensiva: sábado 24/02 de 09 a 12hs.

Horario: 10 a 13hs y 14 a 17hs.


– Lic. Martín Reynoso – Psicoterapia Cognitiva

– Lic. Mercedes Méndez – Psicoterapia Cognitiva

Dirigido a: Profesionales en general


workshop mindfulness febrero

Posterior cortical atrophy: a single case cognitive and radiological follow-up. Esteves S., Ramirez Romero D.A., Torralva T., Martínez Cuitiño M., Herndon S., Couto B., Ibañez A., Manes F. & Roca M. 2018

AUTORES Esteves S., Ramirez Romero D.A., Torralva T., Martínez Cuitiño M., Herndon S., Couto B., Ibañez A., Manes F. & Roca M.
AÑO 2018
JOURNAL Neurocase
VOLUMEN 8 January, 2018
ABSTRACT Posterior cortical atrophy (PCA) is a rare neurodegenerative syndrome characterized by initial predominant visuoperceptual deficits followed by a progressive decline in other cognitive functions. This syndrome has not been as thoroughly described as other dementias, particularly from a neuropsychological evolution perspective with only a few studies describing the evolution of its cognitive progression. In this investigation we review the literature on this rare condition and we perform a 7-year neuropsychological and neuroradiological follow-up of a 64-year-old man with PCA. The subject’s deficits initially appeared in his visuoperceptual skills with later affectation appearing in language and other cognitive functions, this being coherent with the patient’s parieto-temporal atrophy evolution.

La atrofia cortical posterior (ACP) es un síndrome neurodegenerativo raro caracterizado predominantemente por déficits visoperceptivos iniciales seguidos por un progresivo declive en otras funciones cognitivas. Este síndrome no se ha descrito tan minuciosamente como otras demencias, especialmente desde una perspectiva de su evolución neuropsicológica, con sólo unos pocos estudios detallando la evolución de su progresión cognitiva. En esta investigación revisamos la literatura sobre esta rara afección y realizamos un seguimiento neuropsicológico y neuroradiológico de 7 años en un hombre de 64 años con ACP. Los déficits del sujeto aparecieron inicialmente en sus habilidades visoperceptuales y posteriormente se vieron afectados el lenguaje y otras funciones cognitivas, lo cual es coherente con la evolución de la atrofia parieto-temporal del paciente.

Dementia in Latin America. Assessing the present and envisioning the future. Parra MA, Baez S, Allegri R, Nitrini R, Lopera F, Slachevsky A, Custodio N, Lira D, Piguet O, Kumfor F, Huepe D, Cogram P, Bak T, Manes F, Ibanez A. 2018

AUTORES Parra MA, Baez S, Allegri R, Nitrini R, Lopera F, Slachevsky A, Custodio N, Lira D, Piguet O, Kumfor F, Huepe D, Cogram P, Bak T, Manes F, Ibanez A.
AÑO 2018
JOURNAL Neurology
VOLUMEN 5 January, 2018
ABSTRACT The demographic structure of Latin American countries (LAC) is fast approaching that of developing countries, and the predicted prevalence of dementia in the former already exceeds the latter. Dementia has been declared a global challenge, yet regions around the world show differences in both the nature and magnitude of such a challenge. This article provides evidence and insights on barriers which, if overcome, would enable the harmonization of strategies to tackle the dementia challenge in LAC. First, we analyze the lack of available epidemiologic data, the need for standardizing clinical practice and improving physician training, and the existing barriers regarding resources, culture, and stigmas. We discuss how these are preventing timely care and research. Regarding specific health actions, most LAC have minimal mental health facilities and do not have specific mental health policies or budgets specific to dementia. In addition, local regulations may need to consider the regional context when developing treatment and prevention strategies. The support needed nationally and internationally to enable a smooth and timely transition of LAC to a position that integrates global strategies is highlighted. We focus on shared issues of poverty, cultural barriers, and socioeconomic vulnerability. We identify avenues for collaboration aimed to study unique populations, improve valid assessment methods, and generate opportunities for translational research, thus establishing a regional network. The issues identified here point to future specific actions aimed at tackling the dementia challenge in LAC.

El envejecimiento de América Latina (AL) se está acercando rápidamente al de los países en desarrollo, y la prevalencia de la demencia prevista para LA ya supera a estos últimos. Este enfoque de consenso regional de expertos internacionales analiza las barreras impiden la armonización de estrategias para enfrentar el desafío de la demencia en AL. Analizamos la falta de datos epidemiológicos, la práctica clínica y la capacitación, y las barreras existentes con respecto a la pobreza, los estigamas culturales y la vulnerabilidad socioeconómica. Discutimos cómo estos dificultan la atención, el diagnóstico y la investigación en la región. Luego abordamos las acciones de salud específicas, las políticas y presupuestos para la demencia en la region, y las estrategias de tratamiento y prevención. Identificamos vías de colaboración para el estudio de poblaciones únicas en la región, el perfeccionamiento de métodos de evaluación válidos y la generación de oportunidades para la investigación traslacional, fomentando el desarrollo de una red regional que involucre investigadores, clínicos y organizaciones gubernamentales.

Multilevel convergence of interoceptive impairments in hypertension: New evidence of disrupted body–brain interactions. Yoris A, Abrevaya S, Esteves S, Salamone P, Lori N, Martorell M, Legaz A, Alifano F, Petroni A, Sánchez R, Sedeño L, García AM, Ibáñez A. 2017

AUTORES Yoris A, Abrevaya S, Esteves S, Salamone P, Lori N, Martorell M, Legaz A, Alifano F, Petroni A, Sánchez R, Sedeño L, García AM, Ibáñez A.
AÑO 2017
JOURNAL Hum Brain Mapp
VOLUMEN 21 December, 2017
ABSTRACT Interoception, the sensing of visceral body signals, involves an interplay between neural and autonomic mechanisms. Clinical studies into this domain have focused on patients with neurological and psychiatric disorders, showing that damage to relevant brain mechanisms can variously alter interoceptive functions. However, the association between peripheral cardiac-system alterations and neurocognitive markers of interoception remains poorly understood. To bridge this gap, we examined multidimensional neural markers of interoception in patients with early stage of hypertensive disease (HTD) and healthy controls. Strategically, we recruited only HTD patients without cognitive impairment (as shown by neuropsychological tests), brain atrophy (as assessed with voxel-based morphometry), or white matter abnormalities (as evidenced by diffusion tensor imaging analysis). Interoceptive domains were assessed through (a) a behavioral heartbeat detection task; (b) measures of the heart-evoked potential (HEP), an electrophysiological cortical signature of attention to cardiac signals; and (c) neuroimaging recordings (MRI and fMRI) to evaluate anatomical and functional connectivity properties of key interoceptive regions (namely, the insula and the anterior cingulate cortex). Relative to controls, patients exhibited poorer interoceptive performance and reduced HEP modulations, alongside an abnormal association between interoceptive performance and both the volume and functional connectivity of the above regions. Such results suggest that peripheral cardiac-system impairments can be associated with abnormal behavioral and neurocognitive signatures of interoception. More generally, our findings indicate that interoceptive processes entail bidirectional influences between the cardiovascular and the central nervous systems.

La interocepción (o censado de señales viscerales del cuerpo), regula los afectos y la cognición, e implica interacción cerebral y autonómica. Si bien sabemos que la afectación cerebral de regiones interoceptivas impacta en la interocepción cardiaca, poco se sabe acerca de cómo el sistema cardiaco impacta en la neurocognición interoceptiva. Estudiamos a pacientes con estadio temprano de enfermedad hipertensiva (HTD) sin deterioro cognitivo, sin atrofia cerebral (VBM) ni anomalías de la sustancia blanca (DTI) y controles sanos. Los pacientes exhibieron peor rendimiento interoceptivo sus de correlatos cerebrales (medicas corticales cardíacas, volumen y conectividad funcional de ínsula y cingulado). Así, las alteraciones del sistema cardíaco periférico se asocian con patrones anormales neurocognitivos de intercepción.

Intracranial high-γ connectivity distinguishes wakefulness from sleep. Mikulan E, Hesse E, Sedeño L, Bekinschtein T, Sigman M, García MDC, Silva W, Ciraolo C, García AM, Ibáñez A. 2018

AUTORES Mikulan E, Hesse E, Sedeño L, Bekinschtein T, Sigman M, García MDC, Silva W, Ciraolo C, García AM, Ibáñez A.
AÑO 2018
JOURNAL Neuroimage
VOLUMEN 1 April, 2018
ABSTRACT Neural synchrony in the γ-band is considered a fundamental process in cortical computation and communication and it has also been proposed as a crucial correlate of consciousness. However, the latter claim remains inconclusive, mainly due to methodological limitations, such as the spectral constraints of scalp-level electroencephalographic recordings or volume-conduction confounds. Here, we circumvented these caveats by comparing γ-band connectivity between two global states of consciousness via intracranial electroencephalography (iEEG), which provides the most reliable measurements of high-frequency activity in the human brain. Non-REM Sleep recordings were compared to passive-wakefulness recordings of the same duration in three subjects with surgically implanted electrodes. Signals were analyzed through the weighted Phase Lag Index connectivity measure and relevant graph theory metrics. We found that connectivity in the high-γ range (90–120 Hz), as well as relevant graph theory properties, were higher during wakefulness than during sleep and discriminated between conditions better than any other canonical frequency band. Our results constitute the first report of iEEG differences between wakefulness and sleep in the high-γ range at both local and distant sites, highlighting the utility of this technique in the search for the neural correlates of global states of consciousness.

La sincronía neural en la gama alta (90-120 Hz) se ha propuesto como correlato crucial de la conciencia, pero debido a limitaciones metodológicas, esta no es fácil de medir. Comparamos la conectividad entre dos estados globales de conciencia (vigilia y sueño) a través de la registros intracraneales directos, que proporcionan las únicas mediciones de alta frecuencia en el cerebro humano. La conectividad en gama alta en múltiples sectores del cerebro (y su organización en términos de teoría de gráficos), discriminaron la vigilia del sueño mejor que cualquier otra banda y medida. Nuestros resultados constituyen el primer reporte de diferencias entre estados de consciencia  mediante conectividad de gama alta entre regiones locales y distantes.